Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents
US5486625A · kind A · utility
18Cited by
5References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 1994 |
| Grant date | Jan 23, 1996 |
| Priority date | — |
| Expiry date | Jul 8, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D407/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described is a process for preparing chiral compounds of the formula ##STR1## wherein X.sup.1 and X.sup.2 are independently F or Cl, and Y is Cl, Br or I, comprising reacting a triol of the formula ##STR2## wherein X.sup.1 and X.sup.2 are as defined above, with acetone in the presence of a catalyst, then with a halogen selected from Cl.sub.2, Br.sub.2 or I.sub.2, or N-bromosuccinimide or N-iodosuccinimide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.