Pharmaceutical composition comprising BPI proteins
US5488034A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1994 |
| Grant date | Jan 30, 1996 |
| Priority date | — |
| Expiry date | Feb 2, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bactericidal/permeability increasing (BPI) polypeptide pharmaceutical compositions having improved stability and resistance to aggregation, particle formation and precipitation comprising the polypeptide pharmaceutical and poloxamer surfactants alone, or in combination with polysorbate suractants. Preferred BPI polypeptides stabilized are bactericidal/permeability increasing (BPI) protein, biologically active fragments of BPI, and biologically active analogs of BPI.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.