Patent · US Expired

Pharmaceutical composition comprising BPI proteins

US5488034A · kind A · utility

39Cited by
18References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 2, 1994
Grant dateJan 30, 1996
Priority date
Expiry dateFeb 2, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Bactericidal/permeability increasing (BPI) polypeptide pharmaceutical compositions having improved stability and resistance to aggregation, particle formation and precipitation comprising the polypeptide pharmaceutical and poloxamer surfactants alone, or in combination with polysorbate suractants. Preferred BPI polypeptides stabilized are bactericidal/permeability increasing (BPI) protein, biologically active fragments of BPI, and biologically active analogs of BPI.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.