LHRH antagonists having modified aminoacyl residues at positions 5 and 6
US5491217A · kind A · utility
4Cited by
6References
3Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 28, 1994 |
| Grant date | Feb 13, 1996 |
| Priority date | — |
| Expiry date | Jul 28, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of potent LHRH decapeptide antagonists possess N-alkylated aminoacyl residues where the side-chain portion of the residue is a 4-(substimtedamino)phenylalanyl, 4-(substituted-amino)cyclohexylalanyl, or .OMEGA.-(substitutedamino)alkyl group, and additionally the aminoacyl residues at position 5 are N-alkylated on the nitrogen atom of the peptide backbone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.