Tricyclic inhibitors of the GPII.sub.b III.sub.a receptor
US5493020A · kind A · utility
2Cited by
1References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 29, 1993 |
| Grant date | Feb 20, 1996 |
| Priority date | — |
| Expiry date | Jul 29, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A trycylic benzodiazepine derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.