Patent · US Expired

Indole derivatives

US5494928A · kind A · utility

46Cited by
0References
7Claims
0Family size

Assignee

Inventor

Key dates

Filing dateOct 3, 1994
Grant dateFeb 27, 1996
Priority date
Expiry dateOct 3, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention releates to indole derivatives of the formula ##STR1## wherein R.sup.1 to R.sup.4 are, independently, hydrogen, halogen, lower-alkyl, cycloalkyl or trifluoromethyl, R.sup.5 and R.sup.6 are, independently, hydrogen, halogen, lower-alkyl, cycloalkyl, trifluoromethyl, hydroxy or lower-alkoxy and R.sup.7 is hydrogen or lower-alkyl, and pharmaceutically acceptable acid addition salts thereof. The compounds of formula I bind to serotonin receptors and are therefore useful in the treatment and/or prevention of central nervous system disorders, such as depression.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.