Peptide library and screening method
US5498530A · kind A · utility
227Cited by
9References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 15, 1994 |
| Grant date | Mar 12, 1996 |
| Priority date | — |
| Expiry date | Aug 15, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1075
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A random peptide library constructed by transforming host cells with a collection of recombinant vectors that encode a fusion protein comprised of a DNA binding protein and a random peptide and also contain a binding site for the DNA binding protein can be used to screen for novel ligands. The screening method results in the formation of a complex comprising the fusion protein bound to a receptor through the random peptide ligand and to the recombinant DNA vector through the DNA binding protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.