Method of producing halogenated and alpha-aminoalchohols
US5523463A · kind A · utility
5Cited by
5References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 21, 1995 |
| Grant date | Jun 4, 1996 |
| Priority date | — |
| Expiry date | Aug 21, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the manufacture of N-protected .alpha.-aminoketones and N-protected .alpha.-aminoalcohols of the formula ##STR1## wherein X is halogen, one of Q.sup.1 and Q.sup.2 is hydrogen and the other is hydroxy or Q.sup.1 and Q.sup.2 together are oxo, R.sup.1 is an amino protecting group and R.sup.2 is hydrogen or the characterizing group of an .alpha.-aminocarboxylic acid, starting from the corresponding lower alkyl N-protected .alpha.-aminocarboxylates via corresponding lower alkyl N-silyl protected .alpha.-aminocarboxylates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.