Recombinant phospholipase A.sub.2 enzyme
US5527698A · kind A · utility
18Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 22, 1994 |
| Grant date | Jun 18, 1996 |
| Priority date | — |
| Expiry date | Jun 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel DNA and peptide sequences encoding a family of phospholipase A.sub.2 enzymes, with specific activities of approximately 20 .mu.mol/min/mg in the mixed micelle assay. These enzymes are useful in methods for detecting the anti-inflammatory potential of various chemical agents. The invention also details novel methods for determining such potential using the novel sequences, methods for making the novel peptides, and methods for developing new anti-inflammatory drugs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.