Inventor · Carlisle, MA, US

John Knopf

86Patents
22h-index
33Co-inventors
88Inventor score

Filing activity: Feb 28, 1990 → Oct 6, 2022

Most-cited inventions

PatentTitleAreaCited byStatus
US7709605B2 ActRII receptor polypeptides, methods and compositions Chemistry; Metallurgy 112 Active
US7842663B2 Variants derived from ActRIIB and uses therefor Chemistry; Metallurgy 103 Active
US7612041B2 Isolated activin-binding ActRIIa polypeptide comprising the SEQ ID NO: 7 and uses for promoting bone growth Chemistry; Metallurgy 90 Active
US8343933B2 Variants derived from ActRIIB and uses therefor Chemistry; Metallurgy 85 Active
US8178488B2 Methods for increasing thermogenic adipocytes Chemistry; Metallurgy 82 Active
US8252900B2 Actriib-Fc polynucleotides, polypeptides, and compositions Chemistry; Metallurgy 79 Active
US6500853B1 Inhibitors of phospholipase enzymes Chemistry; Metallurgy 57 Expired
US8067360B2 Method for promoting bone growth using activin-ActRIIa antagonists Chemistry; Metallurgy 55 Active
US8629109B2 Method for promoting bone growth using activin-actriia antagonists Chemistry; Metallurgy 53 Active
US7951771B2 Activin-ActRIIa antagonists and uses for promoting bone growth Chemistry; Metallurgy 52 Active
US7501121B2 IL-13 binding agents Chemistry; Metallurgy 50 Expired
US8128933B2 Method of promoting bone growth by an anti-activin B antibody Chemistry; Metallurgy 47 Active
US8703694B2 Methods for increasing thermogenic adipocytes Chemistry; Metallurgy 42 Active
US7960343B2 Activin-ActRIIa antagonists and uses for decreasing or inhibiting FSH secretion Chemistry; Metallurgy 39 Active
US5322776A DNA sequences encoding phospholipase A.sub.2 enzyme and processes for producing enzyme Human Necessities 35 Expired
US9526759B2 Activin-actriia antagonists and uses for treating or preventing breast cancer Physics 34 Active
US9353356B2 Activin-actriia antagonists for treating a follicle-stimulating horomone-secreting pituitary tumor Chemistry; Metallurgy 34 Active
US8367611B2 Activin-actriia antagonists for inhibiting germ cell maturation Chemistry; Metallurgy 33 Active
US5593878A Recombinant phospholipase A.sub.2 enzyme Human Necessities 32 Expired
US5354677A Intracellular phospholipase A.sub.2 enzyme Human Necessities 32 Expired
US8173601B2 Activin-ActRIIa antagonists and uses for treating multiple myeloma Chemistry; Metallurgy 32 Active
US9399669B2 Variants derived from ActRIIB Chemistry; Metallurgy 22 Active
US9138459B2 ACTRIIB-FC polynucleotides, polypeptides, and compositions Chemistry; Metallurgy 20 Active
US5527698A Recombinant phospholipase A.sub.2 enzyme Human Necessities 18 Expired
US10259861B2 Variants derived from ActRIIB and uses therefor Chemistry; Metallurgy 17 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.