Substituted imidazo[4,5-b]pyridines and benzimidazoles

US5527809A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Matthias Muller-Gliemann · Haan, DE
• Jurgen Dressel · Radevormwald, DE
• Peter Fey · Wuppertal, DE
• Rudolf Hanko · Düsseldorf, DE
• Walter Hubsch · Wuppertal, DE
• Thomas Kramer · Wuppertal, DE
• Ulrich Muller · Wuppertal, DE
• Martin Beuck · Milford, US
• Stanislav Kazda · Wuppertal, DE
• Stefan Wohlfeil · Hilden, DE
• Andreas Knorr · Erkrath, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Siegfried Zaiss · Wuppertal, DE

Key dates

• Filing date: Jan 27, 1994
• Grant date: Jun 18, 1996
• Expiry date: Jan 27, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D235/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Substituted imidazo[4,5-b]pyridines and benzimidazoles are prepared by reacting imidazo[4,5-b]pyridines or benzimidazoles with appropriately substituted benzyl halides. The substituted imidazo[4,5-b]pyridines or benzimidazoles can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.