Precision determination for molecular weights
US5528366A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 20, 1994 |
| Grant date | Jun 18, 1996 |
| Priority date | — |
| Expiry date | Oct 20, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/626
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention describes a method by which the precision of the reported molecular weights and radii of chromatographically separated molecules may be estimated. By suitably analyzing both the baseline and peak regions of a chromatogram, one may determine standard deviations of the signals from the various chromatographic detectors used in the analysis. This procedure yields standard deviations of the calculated values of molecular weight and root mean square radius of the separated molecules, as well as standard deviations of the calculated moments of the distribution of molecules. These standard deviations provide an estimate of the precision of the measurements.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.