Ras farnesyl transferase inhibitors
US5532359A · kind A · utility
98Cited by
6References
10Claims
0Family size
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Key dates
| Filing date | Oct 25, 1994 |
| Grant date | Jul 2, 1996 |
| Priority date | — |
| Expiry date | Oct 25, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Benzodiazepine derivatives are disclosed that act as potent inhibitors of ras farnesyl:protein transferase. Pharmaceutical compositions containing these benzodiazepines are provided for treatment of diseases for which inhibition of the ras farnesyl:protein transferase is indicated. Also disclosed are benzazepines of the following general formula (II) having similar utility as the aforementioned benzodiazepines: ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.