Process for the enantioselective hydrogenation of ketosiophorone derivatives
US5543559A · kind A · utility
1Cited by
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6Claims
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Key dates
| Filing date | Jun 8, 1995 |
| Grant date | Aug 6, 1996 |
| Priority date | — |
| Expiry date | Jun 8, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C69/013
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is concerned with a process for the manufacture of optically active compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy, phenyl, benzyl or --NR.sub.2.sup.1, R.sup.1 signifies lower alkyl, phenyl, benzyl or hydrogen and * signifies an optically active center, by asymmetrically hydrogenating an enol derivative of ketoisophorone of the formula ##STR2## wherein R has the significance given above, in the presence of a rhodium complex of an optically active diphosphine ligand.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.