Purification method of crude product
US5547580A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 22, 1995 |
| Grant date | Aug 20, 1996 |
| Priority date | — |
| Expiry date | Mar 22, 2015 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/426
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Disclosed herein is a purification method of a crude product by column chromatography on silica gel or on a vinyl alcohol copolymer. Methanol-containing n-hexane and/or n-hexane-containing methanol is used as an eluent to elute the crude product, thereby obtaining an intended product with high purity and good yield. The solvents recovered from the effluent can be regenerated without any trouble such as rectification and a great cost by mixing them under stirring and then separating the resulting upper and lower layer from each other. The column used can also be reused again and again by washing with methanol. The separation and purification method is excellent in separation efficiency, operation efficiency and economical efficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.