Abruquinone derivatives and their uses
US5563167A · kind A · utility
1Cited by
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6Claims
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Assignee
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Key dates
| Filing date | May 3, 1994 |
| Grant date | Oct 8, 1996 |
| Priority date | — |
| Expiry date | May 3, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/64
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are methods of isolation and purification of active constituents from Hsian-ssu-tsu (Abrus precatorius L.), and the therapeutical applications of the purified compounds. From the cloroform fraction of the methanolic extract of the roots of Abrus precatorius L., Abruquinones A, B, D, E, F, which are shown as Compounds I through V, respectively, as follows: ##STR1## were isolated and identified Pharmacological evaluations showed that these compounds possess an activity to inhibit platelet aggregation, as well as antiinflammatory, and antiallergic activities.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.