Cardiac hypertrophy factor

US5571893A · kind A · utility

Assignees

• Genentech, Inc. · US
• THE REGENTS OF THE UNIV. OF CALIFORNIA · US

Inventors

• Joffre B. Baker · Montara, US
• Kenneth R. Chien · Cambridge, US
• Kathleen King · Pacifica, US
• Diane Pennica · Burlingame, US
• William I. Wood · Hillsborough, US

Key dates

• Filing date: Aug 5, 1994
• Grant date: Nov 5, 1996
• Expiry date: Aug 5, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S930/14
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Isolated CHF, isolated DNA encoding CHF, and recombinant or synthetic methods of preparing CHF are disclosed, These CHF molecules are shown to influence hypertrophic activity and neurological activity. Accordingly, these compounds or their antagonists may be used for treatment of heart failure, arrhythmic disorders, inotropic disorders, and neurological disorders.