Patent · US Expired

Synthesis of oligonucleotides

US5571902A · kind A · utility

128Cited by
9References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 1994
Grant dateNov 5, 1996
Priority date
Expiry dateMay 26, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H23/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Synthetic processes are provided for the solution phase synthesis of oligonucleotides, especially phosphorothioate oligonucleotides, and intermediate compounds useful in the processes. Intermediates having structure ##STR1## are prepared in accord with preferred embodiments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.