Delivery of exogenous DNA sequences in a mammal
US5580859A · kind A · utility
1,158Cited by
7References
20Claims
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Key dates
| Filing date | Mar 18, 1994 |
| Grant date | Dec 3, 1996 |
| Priority date | — |
| Expiry date | Mar 18, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Polynucleotide sequences, comprising DNA and RNA molecules can be directly administered, for example by injection, to tissues, such as muscle, and expressed as a protein, polypeptide or polypeptide. The polynucleotides can be contained within liposomes or the polynucleotides can free from association with transfection-facilitating proteins, viral particles, liposomal formulations, charged lipids and calcium phosphate precipitating agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.