Patent · US Expired

Selectin variants

US5593882A · kind A · utility

18Cited by
2References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 13, 1994
Grant dateJan 14, 1997
Priority date—
Expiry dateJul 13, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/32
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention concerns selectin variants having an amino acid alteration at a site or sites of a selectin lectin domain amino acid sequence within a region defined by binding sites recognized by blocking monoclonal antibodies to the corresponding selectin unaltered in the lectin domain. Nucleotide sequences encoding such variants, expression vectors containing such nucleotide sequences, end host cells transformed with such expression vectors are also within the scope of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.