Texaphyrin solid supports and devices

US5594136A · kind A · utility

Assignees

• Pharmacyclics LLC · US
• The Board of Regents of the University of Texas · US

Inventors

• Jonathan L. Sessler · Austin, US
• Brent L. Iverson · Austin, US
• Vladimir A. Kr al · Austin, US
• Richard E. Thomas · Old Bridge, US
• Darren Magda · Cupertino, US
• Daniel A. Smith · Goshen, US

Key dates

• Filing date: May 3, 1995
• Grant date: Jan 14, 1997
• Expiry date: May 3, 2015

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J2531/38
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides various novel matrix-supported texaphyrins in which a polymeric or solid matrix is covalently modified by the addition of one or more texaphyrins or texaphyrin derivatives. Described are methods of making various polymer-supported texaphyrins, including texaphyrin chromatographic supports, and devices such as catheters, as may be used, for example, in the separation of neutral and anionic species and in applications concerning phosphate ester hydrolysis, other catalytic schemes, MRI, and PDT.