System for interfacing capillary zone electrophoresis and inductively coupled plasma-mass spectrometer sample analysis systems, and method of use
US5597467A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 21, 1995 |
| Grant date | Jan 28, 1997 |
| Priority date | — |
| Expiry date | Feb 21, 2015 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/105
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system for interfacing Capillary Zone Electrophoresis (CZE) systems to Inductively Coupled Plasma-Mass Spectrometer (ICP-MS) sample analysis systems is disclosed. The interface system includes a Sample Introduction Electrophoresis Capillary Tube as an integral part of a modified Direct Injection Nebulizer (DIN) system. During use sample components separated by (CZE) are entered to the modified (DIN) via a sample introduction electrophoresis capillary tube present therein, in which modified (DIN) they are mixed with an entered make-up liquid. The make-up liquid is conductive and serves to make electrophoresis effecting electrical contact to the end of the sample introduction electrophoresis capillary tube in the modified (DIN). The resulting mixture of make-up liquid and separated sample components is nebulized by simultaneous ejection of concentric sample component and make-up liquid mixture and an entered gas flow, to provide a multiplicity of small diameter droplets which are typically injected into an Inductively Coupled Plasma Torch for ionization, prior to entry of resulting ionized sample components to a Mass Spectrometer sample analysis system for detection and analysis th…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.