Patent · US Expired

Quinolone derivatives

US5614532A · kind A · utility

59Cited by
2References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 25, 1994
Grant dateMar 25, 1997
Priority date
Expiry dateMay 25, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A class of 2-(1H)-quinolone derivatives, substituted at the 3-position by an optionally substituted aryl substituent, are selective non-competitive antagonists of NMDA receptors and/or are antagonists of AMPA receptors, and are therefore of utility in the treatment of conditions, such as neurodegenerative disorders, convulsions or schizophrenia, which require the administration of an NMDA and/or AMPA receptor antagonist.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.