Process for preparing oligonucleotides using silyl-containing diamino phosphorous reagents
US5614621A · kind A · utility
68Cited by
5References
22Claims
0Family size
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Key dates
| Filing date | Jul 29, 1993 |
| Grant date | Mar 25, 1997 |
| Priority date | — |
| Expiry date | Jul 29, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Synthetic processes are provided wherein substituted silylalkyl phosphoramidites serve as coupling reagents for preparing phosphate, phosphorothioate, and other phosphorous-containing covalent linkages. Also provided are synthetic intermediates useful in such processes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.