Chimeric papillomavirus-like particles

US5618536A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Douglas R. Lowy · Washington, US
• John T. Schiller · Silver Spring, US
• Heather Greenstone · Silver Spring, US

Key dates

• Filing date: Oct 6, 1994
• Grant date: Apr 8, 1997
• Expiry date: Oct 6, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S977/918
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.