Derivatization of solid supports and methods for oligomer synthesis
US5624711A · kind A · utility
384Cited by
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8Claims
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Key dates
| Filing date | Apr 27, 1995 |
| Grant date | Apr 29, 1997 |
| Priority date | — |
| Expiry date | Apr 27, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B60/14
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and derivatized supports which are useful in solid-phase synthesis of peptides, oligonucleotides or other small organic molecules as well as arrays of ligands. The methods provide means to control the functional site density on a solid support. Some of the derivatized supports are polymer-coated or glycan-coated. Other methods for regenerating the surface of a used ligand array are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.