Patent · US Expired

Dopamine receptor subtype ligands

US5631269A · kind A · utility

26Cited by
3References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 20, 1995
Grant dateMay 20, 1997
Priority date
Expiry dateApr 20, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I) ##STR1## wherein one of X and Y represents nitrogen, and the other of X and Y represents oxygen, sulphur or N--R.sup.2 ; Q represents a substituted five- or six- membered monocyclic heteroaliphatic ring which contains one nitrogen atom as the sole heteroatom and is linked to the five-membered heteroatomic ring containing the moieties X and Y via a carbon atom; as well as substituted 1,3-dioxopropane precursors thereto, are ligands for dopamine receptor subtypes within the body and are therefore useful in the treatment of disorders of the dopamine system, in particular schizophrenia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.