Patent · US Expired

Hairpin ribozymes

US5631359A · kind A · utility

58Cited by
1References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 11, 1994
Grant dateMay 20, 1997
Priority date
Expiry dateOct 11, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/3535
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Hairpin ribozyme lacking a substrate moiety, comprising at least six bases in helix 2 and able to base-pair with a separate substrate RNA, wherein the ribozyme comprises one or more bases 3' of helix 3 able to base-pair with the substrate RNA to form a helix 5 and wherein the said ribozyme can cleave and/or ligate the separate RNA(s) in trans.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.