Ribozyme Pharmaceuticals, Inc.
112Patents
0Active
112Granted
39Portfolio score
Filing activity: May 13, 1992 → Jan 8, 2002
Most-cited patents
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5627053A | 2'deoxy-2'-alkylnucleotide containing nucleic acid | Chemistry; Metallurgy | 481 | Expired |
| US5998203A | Enzymatic nucleic acids containing 5'-and/or 3'-cap structures | Chemistry; Metallurgy | 308 | Expired |
| US6127173A | Nucleic acid catalysts with endonuclease activity | Chemistry; Metallurgy | 156 | Expired |
| US5902880A | RNA polymerase III-based expression of therapeutic RNAs | Chemistry; Metallurgy | 152 | Expired |
| US5972704A | HIV nef targeted ribozymes | Chemistry; Metallurgy | 131 | Expired |
| US6159951A | 2'-O-amino-containing nucleoside analogs and polynucleotides | Chemistry; Metallurgy | 128 | Expired |
| US5583020A | Permeability enhancers for negatively charged polynucleotides | Chemistry; Metallurgy | 122 | Expired |
| US5716824A | 2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes) | Chemistry; Metallurgy | 118 | Expired |
| US5869253A | Method and reagent for inhibiting hepatitis C virus replication | Chemistry; Metallurgy | 94 | Expired |
| US6248878A | Nucleoside analogs | Chemistry; Metallurgy | 92 | Expired |
| US6346398B1 | Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor | Chemistry; Metallurgy | 92 | Expired |
| US6117657A | Non-nucleotide containing enzymatic nucleic acid | Chemistry; Metallurgy | 83 | Expired |
| US5877022A | Ribozymes targeted to APO(a) RNA | Chemistry; Metallurgy | 79 | Expired |
| US6566127B1 | Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor | Chemistry; Metallurgy | 76 | Expired |
| US6395713B1 | Compositions for the delivery of negatively charged molecules | Chemistry; Metallurgy | 74 | Expired |
| US5610054A | Enzymatic RNA molecule targeted against Hepatitis C virus | Chemistry; Metallurgy | 72 | Expired |
| US5804683A | Deprotection of RNA with alkylamine | Emerging Cross-Sectional Technologies | 69 | Expired |
| US5646042A | C-myb targeted ribozymes | Chemistry; Metallurgy | 60 | Expired |
| US5631359A | Hairpin ribozymes | Chemistry; Metallurgy | 58 | Expired |
| US5525468A | Assay for Ribozyme target site | Chemistry; Metallurgy | 57 | Expired |
| US5496698A | Method of isolating ribozyme targets | Chemistry; Metallurgy | 56 | Expired |
| US6146886A | RNA polymerase III-based expression of therapeutic RNAs | Chemistry; Metallurgy | 54 | Expired |
| US6469158B1 | Synthesis, deprotection, analysis and purification of RNA and ribozymes | Emerging Cross-Sectional Technologies | 53 | Expired |
| US5831071A | Synthesis deprotection analysis and purification of RNA and ribozymes | Emerging Cross-Sectional Technologies | 53 | Expired |
| US6022962A | Hairpin ribozymes | Chemistry; Metallurgy | 51 | Expired |
Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.