Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
US5637481A · kind A · utility
130Cited by
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22Claims
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Key dates
| Filing date | Sep 13, 1993 |
| Grant date | Jun 10, 1997 |
| Priority date | — |
| Expiry date | Sep 13, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/705
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides an expression vector encoding monospecific or bispecific fusion protein. In one embodiment the expression vector encodes a monospecific fusion protein, which vector comprises a recombinant monospecific single chain cassette comprising a DNA sequence encoding a first binding domain capable of binding a cell surface antigen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.