Inventor · Shoreline, WA, US

Jeffrey A. Ledbetter

80Patents
37h-index
44Co-inventors
88Inventor score

Filing activity: Oct 19, 1984 → Oct 22, 2024

Most-cited inventions

PatentTitleAreaCited byStatus
US5500362A Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 777 Expired
US5844095A CTLA4 Ig fusion proteins Chemistry; Metallurgy 219 Expired
US5434131A Chimeric CTLA4 receptor and methods for its use Emerging Cross-Sectional Technologies 194 Expired
US6132992A Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell Physics 172 Expired
US5977318A CTLA4 receptor and uses thereof Emerging Cross-Sectional Technologies 151 Expired
US5677180A Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 131 Expired
US5637481A Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell Physics 130 Expired
US5580756A B7IG fusion protein Emerging Cross-Sectional Technologies 130 Expired
US5521288A CD28IG fusion protein Emerging Cross-Sectional Technologies 118 Expired
US5721108A Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 113 Expired
US8409577B2 Single chain multivalent binding proteins with effector function Chemistry; Metallurgy 111 Active
US5770197A Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules Emerging Cross-Sectional Technologies 111 Expired
US6120767A Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 109 Expired
US6010902A Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity Chemistry; Metallurgy 102 Expired
US5851795A Soluble CTLA4 molecules and uses thereof Emerging Cross-Sectional Technologies 99 Expired
US5885796A CTLA4 receptor and uses thereof Emerging Cross-Sectional Technologies 98 Expired
US5773253A MYPPPY variants of CTL A4 and uses thereof Chemistry; Metallurgy 95 Expired
US5916560A Methods for inhibiting an immune response by blocking the GP39/CD40 and CTLA4/CD28/B7 pathways and compositions for use therewith Chemistry; Metallurgy 91 Expired
US7754208B2 Binding domain-immunoglobulin fusion proteins Chemistry; Metallurgy 89 Expired
US5968510A CTLA4 receptor and uses thereof Emerging Cross-Sectional Technologies 88 Expired
US6623940B1 Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell Physics 80 Expired
US6090914A CTLA4/CD28Ig hybrid fusion proteins and uses thereof Chemistry; Metallurgy 79 Expired
US5709859A Mixed specificity fusion proteins Emerging Cross-Sectional Technologies 75 Expired
US6893625B1 Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 66 Expired
US5885579A CTLA4 receptor and uses thereof Emerging Cross-Sectional Technologies 64 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.