Production of fibrinogen in transgenic animals
US5639940A · kind A · utility
30Cited by
2References
33Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 3, 1994 |
| Grant date | Jun 17, 1997 |
| Priority date | — |
| Expiry date | Mar 3, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Materials and methods for producing fibrinogen in transgenic non-human mammals are disclosed. DNA segments encoding A.alpha., B.beta. and .gamma. chains of fibrinogen are introduced into the germ line of a non-human mammal, and the mammal or its female progeny produces milk containing fibrinogen expressed from the introduced DNA segments. Non-human mammalian embryos and transgenic non-human mammals carrying DNA segments encoding heterologous fibrinogen polypeptide chains are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.