Methods of identifying drugs with selective effects against cancer cells
US5645988A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 15, 1994 |
| Grant date | Jul 8, 1997 |
| Priority date | — |
| Expiry date | Jun 15, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention involves a method of identifying drugs which selectively inhibit the growth of particular cancer cells, which method comprises: (a) contacting with the drug at least two cancer cells derived from the same type of biological material, wherein the cancer cells differ as to the presence of a particular DNA sequence, (b) measuring the effect of the drug on the growth of the cancer cells, and (c) determining whether there is a correlation between the effect of the drug on the cancer cells and the presence or absence of the DNA sequence in the cancer cells. The present invention further involves the use of such drugs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.