Mono- and bicyclic DNA gyrase inhibitors
US5665746A · kind A · utility
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38Claims
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Assignee
Inventors
Key dates
| Filing date | Oct 11, 1995 |
| Grant date | Sep 9, 1997 |
| Priority date | — |
| Expiry date | Oct 11, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a compound of the formula ##STR1## wherein X.sup.1, R.sup.1, R.sup.2, OP, R.sup.3, R.sup.4, R.sup.5, R.sup.6, and R.sup.0 are as described herein, and their pharmaceutically acceptable salts thereof carrying an acidic andr basic substituent. The compound of formula I as well as their pharmaceutically acceptable salts inhibit DNA gyrase activity in bacteria and possess antibiotic, especially antibacterial activity against microorganisms and can be used in the control or prevention of infectious diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.