Method for controlling hyperproliferative diseases
US5670151A · kind A · utility
15Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1991 |
| Grant date | Sep 23, 1997 |
| Priority date | — |
| Expiry date | Dec 10, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/6819
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for controlling the overgrowth of hyperproliferating cells in the presence of non-proliferating cells by exposing the hyperproliferating cells to a toxin conjugate that has a binding region that binds to an internalizable element of the hyperproliferating cell and a toxic moiety bound thereto is provided. The toxin conjugate may be a monoclonal antibody to transferrin receptor. Such toxin conjugates will have use in controlling hyperproliferative diseases of the integument and the eye.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.