Sugar modified oligonucleotides that detect and modulate gene expression
US5670633A · kind A · utility
602Cited by
6References
3Claims
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Key dates
| Filing date | Mar 5, 1992 |
| Grant date | Sep 23, 1997 |
| Priority date | — |
| Expiry date | Mar 5, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16322
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are provided for the treatment and diagnosis of diseases amenable to modulation of the production of selected proteins. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least two of the 2'-deoxyfuranosyl moieties of the nucleoside unit is modified. Treatment of HIV, herpes virus, papillomavirus and other infections is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.