Synthetic unrandomization of oligomer fragments
US5672472A · kind A · utility
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3References
64Claims
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Key dates
| Filing date | Feb 22, 1994 |
| Grant date | Sep 30, 1997 |
| Priority date | — |
| Expiry date | Feb 22, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/70
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods useful for the determination of oligomers which have specific activity for a target molecule from a pool of primarily randomly assembled subunits are provided. The disclosed methods involve repeated syntheses of increasingly simplified sets of oligomers coupled with selection procedures for determining oligomers having the highest activity. Freedom from the use of enzymes allows the application of these methods to any molecules which can be oligomerized in a controlled fashion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.