Nonpeptidyl integrin inhibitors having specificity for the GPII.sub.b III.sub.a receptor
US5674863A · kind A · utility
10Cited by
11References
7Claims
0Family size
Assignee
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Key dates
| Filing date | May 26, 1995 |
| Grant date | Oct 7, 1997 |
| Priority date | — |
| Expiry date | May 26, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D267/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.