Method and apparatus for reducing band broadening in chromatographic detectors
US5676830A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 12, 1996 |
| Grant date | Oct 14, 1997 |
| Priority date | — |
| Expiry date | Apr 12, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/74
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A capillary tube used to transfer a liquid sample into a detection cell following separation by a chromatographic system is modified by plugging or otherwise severely restricting its flow. Near its plugged end, said tube is drilled to provide a plurality of holes or ports perpendicular thereto and penetrating into the central flowing core of said tube so as to direct outflow from the tube perpendicularly therefrom. The outer diameter of this so-modified capillary tube is selected to be of a size comparable to, though smaller than, the detection cell diameter into which it transfers the flowing sample. In this manner, fluid transferred into a detection cell by said modified capillary tube will be split into a plurality of smaller streams flowing outwardly therefrom and striking the adjacent detector cell walls almost immediately. Because of the close proximity of the emerging split streams to the walls of the detection cell, the eddies produced thereby will be very small and the contents of the detection cell will be homogenized rapidly.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.