Cleavage site blocking antibody to prohormone proteins and uses thereof
US5677182A · kind A · utility
6Cited by
1References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 18, 1995 |
| Grant date | Oct 14, 1997 |
| Priority date | — |
| Expiry date | Apr 18, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/809
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Cleavage site blocking antibody that binds to prohormones, preferable Tumor Necrosis Factor, thereby preventing the formation of prohormone fragment(s) by proteolysis of the prohormone, and uses of the antibody including prophylactic and therapeutic methods to treat disease, and diagnostic assays for determining the amount of the prohormone and prohormone fragments present in a patients body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.