Gene encoding cardiac hypertrophy factor

US5679545A · kind A · utility

Assignees

• Genentech, Inc. · US
• The Regents of the University of California · US

Inventors

• Joffre B. Baker · Montara, US
• Kenneth R. Chien · Cambridge, US
• Kathleen King · Pacifica, US
• Diane Pennica · Burlingame, US
• William I. Wood · Hillsborough, US

Key dates

• Filing date: May 17, 1995
• Grant date: Oct 21, 1997
• Expiry date: May 17, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S930/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isolated CT-1, isolated DNA encoding CT-1, and recombinant or synthetic methods of preparing CT-1 are disclosed. These CT-1 molecules are shown to influence hypertrophic activity and neurological activity. Accordingly, these compounds or their antagonists may be used for treatment of heart failure, arrhythmic disorders, inotropic disorders, and neurological disorders.