Methods for producing polypeptide metal binding sites and compositions thereof
US5679548A · kind A · utility
72Cited by
0References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 1993 |
| Grant date | Oct 21, 1997 |
| Priority date | — |
| Expiry date | Jun 14, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention describes methods for producing metal binding sites on polypeptides, and particularly for producing metal binding sites within the CDR regions of immunoglobulin heavy or light chains that are displayed on the surface of filamentous phage particles. The invention also describes oligonucleotides useful for preparing the metal binding sites, and human monoclonal antibodies produced by the present methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.