Patent · US Expired

Benzodiazepine derivatives

US5681833A · kind A · utility

39Cited by
0References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 20, 1994
Grant dateOct 28, 1997
Priority date
Expiry dateSep 20, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D403/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of Formula (I), and salts and prodrugs thereof, wherein said formula, R.sup.1 represents certain optionally substituted alkyl or C.sub.3-7 cycloalkyl; R.sup.2 represents (II) or (III), where m is 0, 1, 2 or 3; R.sup.9 is H or C.sub.1-6 alkyl; R.sup.10 is imidazolyl, triazolyl or tetrazolyl, and R.sup.11 is H, C.sub.1-6 alkyl or halo; R.sup.3 is C.sub.1-6 alkyl, halo or NR.sup.6 R.sup.7 ; R.sup.4 is C.sub.1-7 alkyl, C.sub.3-10 cycloalkyl, C.sub.3-10 cycloalkylC.sub.1-4 alkyl, C.sub.6-10 bicycloalkyl, optionally substituted aryl, or NR.sub.12 R.sub.13 ; R.sup.5 is H or C.sub.1-4 alkyl; n is 0, 1, 2 or 3; which are CCK and/or gastrin antagonists useful in therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.