Nucleic acid ligands of tissue target
US5688935A · kind A · utility
58Cited by
1References
13Claims
0Family size
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Key dates
| Filing date | May 3, 1995 |
| Grant date | Nov 18, 1997 |
| Priority date | — |
| Expiry date | May 3, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/976
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to peripheral blood mononuclear cells (PBMC), fibrin clots, and carotid arteries are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.