Patent assignee · US · COMPANY

NeXstar Pharmaceuticals, Inc.

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134Patents
0Active
134Granted
42Portfolio score

Filing activity: Jul 23, 1991 → Nov 23, 1999

Most-cited patents

PatentTitleAreaCited byStatus
US5637459A Systematic evolution of ligands by exponential enrichment: chimeric selex Physics 270 Expired
US5580737A High-affinity nucleic acid ligands that discriminate between theophylline and caffeine Physics 254 Expired
US5683867A Systematic evolution of ligands by exponential enrichment: blended SELEX Physics 227 Expired
US5660985A High affinity nucleic acid ligands containing modified nucleotides Physics 219 Expired
US5595877A Methods of producing nucleic acid ligands Physics 201 Expired
US5705337A Systematic evolution of ligands by exponential enrichment: chemi-SELEX Physics 199 Expired
US5958691A High affinity nucleic acid ligands containing modified nucleotides Physics 185 Expired
US5496938A Nucleic acid ligands to HIV-RT and HIV-1 rev Physics 171 Expired
US5861254A Flow cell SELEX Chemistry; Metallurgy 161 Expired
US6011020A Nucleic acid ligand complexes Physics 147 Expired
US5989823A Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction Chemistry; Metallurgy 146 Expired
US6147204A Nucleic acid ligand complexes Physics 134 Expired
US5554728A Lipid conjugates of therapeutic peptides and protease inhibitors Chemistry; Metallurgy 130 Expired
US5476766A Ligands of thrombin Physics 125 Expired
US6028186A High affinity nucleic acid ligands of cytokines Physics 113 Expired
US6127119A Nucleic acid ligands of tissue target Physics 111 Expired
US5472841A Methods for identifying nucleic acid ligands of human neutrophil elastase Physics 109 Expired
US5786462A High affinity ssDNA ligands of HIV-1 reverse transcriptase Physics 107 Expired
US5696249A Nucleic acid ligands Physics 107 Expired
US5843653A Method for detecting a target molecule in a sample using a nucleic acid ligand Physics 106 Expired
US6083696A Systematic evolution of ligands exponential enrichment: blended selex Chemistry; Metallurgy 106 Expired
US5543293A DNA ligands of thrombin Physics 105 Expired
US5817785A Methods of producing nucleic acid ligands Physics 103 Expired
US6110900A Nucleic acid ligands Physics 102 Expired
US6168778A Vascular endothelial growth factor (VEGF) Nucleic Acid Ligand Complexes Physics 102 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.