Patent · US Expired

Adenovirus for delivering foreign DNA into higher eukaryotic cells

US5693509A · kind A · utility

67Cited by

2References

13Claims

0Family size

Assignees

Boehringer Ingelheim International GmbH · DE
Genentech, Inc. · US

Inventors

Matthew Cotten · Wien, AT
Ernst-Werner Wagner · Langenzersdorf, AT

Key dates

Filing date	Sep 29, 1995
Grant date	Dec 2, 1997
Priority date	—
Expiry date	Sep 29, 2015

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2810/80
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Viruses or cells are targeted for selective internalization into a target in vive. A molecule Specific for a receptor on the surface of the target cell is introduced onto the surface of the virus or cell. The modified virus or cell binds the receptor in vive and is internalized by the target cell. The method provides vectors for selective delivery of nucleic acids to specific cell types in vivo and a means to alter the tropism of an infectious agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.