Methods of producing antigen forks
US5705614A · kind A · utility
17Cited by
3References
1Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 1, 1995 |
| Grant date | Jan 6, 1998 |
| Priority date | — |
| Expiry date | Mar 1, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a class of molecules called "antigen forks" that inhibit cell growth. These antigen forks possess separate binding elements for two different cell surface antigens and are believed to heterologously crosslink the antigens by binding to them. The two antigens recognized by an antigen fork differ in at least one cellular functional quality, but are simultaneously expressed on the surface of at least one cell type targeted for killing or growth inhibition. The present invention also relates to a method of assay to determine which antibodies may be useful in the preparation of antigen forks.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.