Tricyclic inhibitors of the GPII.sub.b III.sub.a receptor
US5705890A · kind A · utility
3Cited by
3References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1994 |
| Grant date | Jan 6, 1998 |
| Priority date | — |
| Expiry date | Sep 26, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A tricylic benzodiazepine derivative that acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.