Methods for detecting Hepatitis C virus using polynucleotides specific for same

US5712088A · kind A · utility

Assignee

• Chiron Corporation · US

Inventors

• Michael Houghton · Berkeley, US
• Qui-Lim Choo · Corona, US
• George Kuo · San Francisco, US
• Amy J. Weiner · Berkeley, US
• Jang Han · Lafayette, US
• Michael S. Urdea · Alamo, US
• Bruce D. Irvine · Glendora, US
• Janice A. Kolberg · Hercules, US

Key dates

• Filing date: May 15, 1995
• Grant date: Jan 27, 1998
• Expiry date: May 15, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2770/24222
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A new virus, Hepatitis C virus (HCV), which has proven to be the major etiologic agent of blood-borne NANBH, was discovered by Applicant. Reagents for isolating, amplifying, and detecting HCV polynucleotides are provided. These reagents are oligomers containing polynucleotide sequences which are capable of forming hybrid structures with HCV target polynucleotide sequences.