Substituted pyridines and 2-oxo-1,2-dihydropyridines

US5712296A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Peter Fey · Wuppertal, DE
• Jurgen Dressel · Radevormwald, DE
• Rudolf Hanko · Düsseldorf, DE
• Walter Hubsch · Wuppertal, DE
• Thomas Kramer · Wuppertal, DE
• Ulrich Muller · Wuppertal, DE
• Matthias Muller-Gliemann · Haan, DE
• Martin Beuck · Milford, US
• Hilmar Bischoff · Wuppertal, DE
• Stefan Wohlfeil · Hilden, DE
• Dirk Denzer · Wuppertal, DE
• Stanislav Kazda · Wuppertal, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Andreas Knorr · Erkrath, DE
• Siegfried Zaiss · Wuppertal, DE

Key dates

• Filing date: Oct 27, 1995
• Grant date: Jan 27, 1998
• Expiry date: Oct 27, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted pyridines and 2-oxo-1,2-dihydropyridines are prepared by reaction of correspondingly substituted halogenobenzenes with tetrazolylboronic acids. The substituted pyridines and 2-oxo-1,2-dihydropyridines according to the invention can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.