Systematic evolution of ligands by exponential enrichment: tissue selex
US5712375A · kind A · utility
98Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 3, 1995 |
| Grant date | Jan 27, 1998 |
| Priority date | — |
| Expiry date | May 3, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/976
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.